Resident Evil executive producer Jun Takeuchi has revealed that the series' overarching narrative has a definite conclusion, which could come as soon as the next 10 years. This news may be disappointing for fans who were hoping to see the series continue indefinitely. Takeuchi explained that the team had expanded on the series' story with each new game, and that a 10-year strategy was crafted during the planning stages for Resident Evil 2 Remake. He believes that the first 10 years have come to a close with the release of Resident Evil Requiem this year, and that the conclusion will follow in the next decade.

Capcom has several Resident Evil games in the works, although Takeuchi declined to provide further details, saying it would spoil the fun for everyone. The company has already seen significant success with the series, with Resident Evil 2 Remake being the best-selling game in the franchise and Resident Evil Requiem passing $500 million in revenue after its release earlier this year. The series has also been a driving factor in console sales within Japan.